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Found 6,435 Results / Page 1 of 429
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Chiral dual-annihilator model for controllable photon upconversion and multi-dimensional optical modulation
2025 / Nature CommunicationsTriplet-triplet annihilation photon upconversion seeks efficient conversion of low-energy photons to high-energy emission. However, the triplet-triplet annihilation photon upconversion system faces limitations in emission gamut because efficient triplet-triplet energy transfer between sensitizer and annihilator relies on triplet energy matching, making it challen...
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Structural insights into light harvesting by antenna-containing rhodopsins in marine Asgard archaea
2025 / Nature MicrobiologyAquatic bacterial rhodopsin proton pumps harvest light energy for photoheterotrophic growth and are known to contain hydroxylated carotenoids that expand the wavelengths of light utilized, but these have not been characterized in marine archaea. Here, by combining a marine chromophore extract with purified archaeal rhodopsins identified in marine metagenomes, we ...
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The rechargeable battery using uranium as an active material
2025 / Scientific ReportsWe first demonstrate a nonaqueous rechargeable battery using uranium and iron as active materials. This uranium-iron battery achieves an open-circuit voltage of approximately 1.3 V, exhibits stable cycling performance, and delivers a good Coulombic efficiency of 86 ± 2%. These characteristics suggest a promising avenue for utilizing depleted ur...
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Functionalization of cotton fabric using bio-organic heat storage materials for human protection and thermal comfortability
2025 / Scientific ReportsIn this work, the synthesis of smart hosting materials from modified gelatin with different fatty acids (myristic acid, palmitic acid, and stearic acid) has been observed and characterized. Coconut oil was used as a natural phase change material (PCM) and octadecanol was used as an organic phase change material. Different concentrations of Phase change materials we...
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Efficacy of bottle gourd (Lagenaria siceraria) leaf extract in protecting against cabbage looper (Trichoplusia ni) (Lepidoptera: Noctuidae) infestation
2025 / Crop HealthCabbage (Brassica oleracea L.) crops are frequently attacked by cabbage looper larvae (Trichoplusia ni), which severely reduce cabbage production. This experiment was conducted in the late spring crop season from April 15, 2024, to August 20, 2024, at the Field Science Center for the Northern Biosphere, Hokkaido University, Japan. In this study, the efficacy of an ...
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Rational Design Principles for De Novo α-Helical Peptide Barrels with Dynamic Conductive Channels
2025 / Journal of the American Chemical SocietyDespite advances in peptide and protein design, the rational design of membrane-spanning peptides that form conducting channels remains challenging due to our imperfect understanding of the sequence-to-structure relationships that drive membrane insertion, assembly, and conductance. Here, we describe the design and computational and experimental characterization of...
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Cathelicidin-BF: A Potent Antimicrobial Peptide Leveraging Charge and Phospholipid Recruitment against Multidrug-Resistant Clinical Bacterial Isolates
2025 / Journal of the American Chemical SocietyCathelicidin-BF (CatBF) is a LL-37 homologous antimicrobialpeptide(AMP) isolatedfromBungarus fasciatuswith anexceptional portfolioof antimicrobial, antiviral, antifungal, and anticancer activities. Contrary tomanyAMPs, it showeda good pharmacologicalprofilewithahalf-lifeofat least1hinserumand efficacyagainstbacterial infectionsinmice.Toevaluateitspotential against ...
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Targeted delivery of doxorubicin to B-cell lymphoma using monoclonal antibody-functionalized Chaetoceros biosilica
2025 / Scientific ReportsThe use of biogenic nanoparticles as targeted drug delivery systems has gained increasing attention for improving anticancer therapies. This study investigates the effectiveness of porous biosilica derived from the diatom Chaetoceros sp., functionalized with hydrophilic GPTMS, labeled with CD-19 antibody, and loaded with doxorubicin in targeting Raji cells, a B l...
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Central-to-Axial-to-Central Chirality Transfer in the Au(I)-Catalyzed Cycloisomerization of Propargyl Vinyl Ethers to Cyclopentadienes
2025 / The Journal of Organic ChemistryAn easy approach to the enantioselective synthesis of five-, six-, and seven-membered ring-fused cyclopentadienes (85–99% ee) is based on the Au(I)-catalyzed cycloisomerization of enantiomerically pure or enriched propargyl vinyl ethers, which occurs with complete central-to-axial-to-central chirality transfer. DFT calculations show that the formation of a no...
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A self-assembled protein β-helix as a self-contained biofunctional motif
2025 / Nature CommunicationsNature constructs matter by employing protein folding motifs, many of which have been synthetically reconstituted to exploit function. A less understood motif whose structure-function relationships remain unexploited is formed by parallel β-strands arranged in a helical repetitive pattern, termed a β-helix. Herein we reconstitute a protein β-helix ...
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Enantiomeric diarylheptanoids from Ottelia acuminata var. acuminata and their α-glucosidase inhibitory activity
2025 / Natural Products and BioprospectingOtteacumienes G–K (1–5), five pairs of enantiomeric diarylheptanoids, along with one undescribed diarylheptanoid glycoside and one new lignan, were isolated from Ottelia acuminata var. acuminata. Compounds 1–5 were identified as five pairs of enantiomers and their structural configurations were determined through a combination of spectroscopic ana...
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Rational search for natural antimicrobial compounds: relevance of sesquiterpene lactones
2025 / Natural Products and BioprospectingAntimicrobial resistance is one of the most pressing global health challenges, as many pathogens are rapidly evolving to evade existing treatments. Despite this urgent need for new solutions, natural plant-derived compounds remain relatively underexplored in the development of antimicrobial drugs. This report highlights an innovative approach to discovering potent ...
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Development of an innovative cost-effective hemostatic material based on electrospun polyacrylonitrile/exfoliated bentonite/calcium chloride nanocomposite
2025 / Scientific ReportsAnti-hemorrhage nanomaterials are emerging as a promising alternative to traditional materials such as cotton and medical gauze, which often exhibit limited hemostatic properties and excessive adhesion to wound surfaces. This study presents the development of hemostatic nanofiber mats fabricated from polyacrylonitrile (PAN) via electrospinning. The incorporation ...
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Fabrication and application of naturally sourced nano-pigments based on algal biomass in multifunctional coatings
2025 / Scientific ReportsThis work aims to synthesize economical and eco-friendly naturally sourced nano-pigments with bright colors, antimicrobial activity, and thermal stability from algal cells cultivated in wastewater, which are then harvested, dried, and converted into algal biomass (AB). Algal biomass (AB) was covered by a very thin nano-layer of either zinc ferrite or cerium ferri...
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Preparation of antimicrobial polymeric composites using defective silk cocoons and moringa seed oil as additives for polyvinyl chloride
2025 / Scientific ReportsIn this work, novel polymeric blends were prepared from polyvinyl chloride (PVC) and silkworm cocoon waste (SCW), that were defective cocoons excluded during the silk-making process in the ratio 50:50 w/w. These blends were incorporated with moringa seed oil (MSO) as a bio-based plasticizer with different concentrations (1, 2, and 3%) to obtain a final bioplastic...
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