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Found 4,464 Results / Page 3 of 298
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Exceptional Thermal Conductivity in Printed Dielectrics through Compositional and Microstructural Design
2025 / Advanced MaterialsAs electronic devices become simultaneously more powerful and compact, thermal management is increasingly critical. Optimizing components like heatsinks is increasingly required, which has recently leveraged additive manufacturing. There is growing demand to move away from incumbent metallic materials for dielectric materials that are electrically insulative and tr...
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Ecofriendly first-derivative synchronous fluorometric method for simultaneous determination of atorvastatin and aspirin in pharmaceutical preparations
2025 / Scientific ReportsThe combination of atorvastatin (ATO) and aspirin (ASP) is widely prescribed for preventing cardiovascular diseases, particularly in individuals at risk of atherosclerosis and myocardial infarction. This study aims to develop and validate an eco-friendly spectrofluorimetric method using the first-derivative synchronous fluorescence (FDSSF) technique (Δ&lamb...
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Structural basis for the human SENP5’s SUMO isoform discrimination
2025 / Nature CommunicationsPost-translational SUMO modification is a widespread mechanism for regulating protein function within cells. In humans, SUMO-conjugated proteins are partially regulated by the deconjugating activity of six SENP family members. The proteolytic activity of these enzymes resides within a conserved catalytic domain that exhibits specificity for the two primary SUMO i...
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Functionalization of cotton fabric using bio-organic heat storage materials for human protection and thermal comfortability
2025 / Scientific ReportsIn this work, the synthesis of smart hosting materials from modified gelatin with different fatty acids (myristic acid, palmitic acid, and stearic acid) has been observed and characterized. Coconut oil was used as a natural phase change material (PCM) and octadecanol was used as an organic phase change material. Different concentrations of Phase change materials we...
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Efficacy of bottle gourd (Lagenaria siceraria) leaf extract in protecting against cabbage looper (Trichoplusia ni) (Lepidoptera: Noctuidae) infestation
2025 / Crop HealthCabbage (Brassica oleracea L.) crops are frequently attacked by cabbage looper larvae (Trichoplusia ni), which severely reduce cabbage production. This experiment was conducted in the late spring crop season from April 15, 2024, to August 20, 2024, at the Field Science Center for the Northern Biosphere, Hokkaido University, Japan. In this study, the efficacy of an ...
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Engineering flexible superblack materials
2025 / Nature CommunicationsFlexible superblack materials are crucial for minimizing stray light, complicating object identification, and serving as low reflectance standards. However, the applications of existing superblack materials are limited due to challenges related to cost-effective scalable manufacturing, surface durability, and material conformability. Furthermore, existing fabrica...
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Albumin Corona Overturns Long-Acting Behaviors of Myristic Acid-Conjugated Quetiapine Nanosuspension
2025 / Advanced Healthcare MaterialsThis work aimed to investigate the interaction of a self-assembled myristic acid-conjugated quetiapine nanosuspension (QMN) with human serum albumin and its overturning effect on QMN’s long-acting performance. Albumin corona formation modified the physicochemical properties and pharmacokinetic profile of QMN by overturning its pH-responsiveness and nano-aggre...
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The Role of Dynamic Solvent Swelling in Electrochemical Doping of Semiconducting Polymers
2025 / Advanced Materials InterfacesSemiconducting polymers are of interest due to their solution processibility and broad electronic applications. Electrochemistry allows these wide bandgap semiconductors to be converted to conducting polymers by doping such polymers at various potentials. When polymers are p-doped to improve their conductivity via electrochemical oxidation, various positively-charg...
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Unveiling the Capacity Boosting Mechanism of the MoS2 Electrode by Focusing on the Under Potential Deposition in All-Solid-State Batteries Prepared by One-Pot One-Step Liquid Phase Mixing
2025 / Advanced Sustainable SystemsMolybdenum disulfide (MoS2) is a high theoretical capacity (670 mAh g−1) electrode material. However, several researchers report that rechargeable batteries using MoS2 often exhibit a discharge capacity of 1000 mAh g−1 that exceeds the theoretical discharge capacity. Although various speculations are proposed, only a limited number of reports have provi...
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Rational Design Principles for De Novo α-Helical Peptide Barrels with Dynamic Conductive Channels
2025 / Journal of the American Chemical SocietyDespite advances in peptide and protein design, the rational design of membrane-spanning peptides that form conducting channels remains challenging due to our imperfect understanding of the sequence-to-structure relationships that drive membrane insertion, assembly, and conductance. Here, we describe the design and computational and experimental characterization of...
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Mechanically-Tunable and Full-Color Circularly Polarized Long-Lived Phosphorescence in Chiral Superstructure Elastomers
2025 / Advanced MaterialsDeveloping full-color circularly polarized organic ultralong room-temperature phosphorescence (CP-OURTP) materials with high dissymmetry factor (glum) holds significant promise for diverse optoelectronic applications. Controlling glum values is crucial for enhancing the performance and functionality of these materials, as it directly influences their chiroptical ...
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Highly Textured Sn-Doped Ga2O3 Epilayers for Economically Viable Solar-Blind Ultraviolet Photodetectors with High Responsivity
2025 / Advanced Optical MaterialsThe design and development of solar-blind photodetectors utilizing ultrawide bandgap semiconductors have garnered significant attention due to their extensive utility in specialty commercial sectors. Solar-blind photodetectors that display excellent photosensitivity, fast response time and are produced using cost-effective fabrication steps will fulfill the perfo...
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Cathelicidin-BF: A Potent Antimicrobial Peptide Leveraging Charge and Phospholipid Recruitment against Multidrug-Resistant Clinical Bacterial Isolates
2025 / Journal of the American Chemical SocietyCathelicidin-BF (CatBF) is a LL-37 homologous antimicrobialpeptide(AMP) isolatedfromBungarus fasciatuswith anexceptional portfolioof antimicrobial, antiviral, antifungal, and anticancer activities. Contrary tomanyAMPs, it showeda good pharmacologicalprofilewithahalf-lifeofat least1hinserumand efficacyagainstbacterial infectionsinmice.Toevaluateitspotential against ...
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A Multifunctional Enzyme Cascade Catalytic Nanoplatform for Effective Synergistic Therapy of Rheumatoid Arthritis
2025 / Advanced Functional MaterialsInsufficient oxygen supply and elevated levels of reactive oxygen species (ROS) in rheumatoid arthritis (RA) joints synergistically exacerbate inflammation and accelerate disease progression. In this study, a hybrid nanoassembly composed of superoxide dismutase (SOD) and catalase (CAT) conjugated within a single poly(ε-caprolactone) (PCL) nanoparticle is ...
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Superior forward osmosis cellulosic membrane for water desalination and brine concentration
2025 / Scientific ReportsBrine is an inevitable product of desalination plants and various industrial sectors. The appropriate disposal of brines and their highly concentrated salts and other diverse contaminants is a critical environmental challenge to most plants. Recently, the FO process is gaining attention as a viable alternative to conventional brine concentration methods, primaril...
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